High-Frequency Intracerebral EEG Activity (100?500 Hz) Following Interictal Spikes

Interictal high-frequency oscillations (100-500 Hz) in the intracerebral EEG of epileptic patients.

Interictal fast oscillations between 100 and 500 Hz have been reported in signals recorded from implanted microelectrodes in epileptic patients and experimental rat models. Oscillations between 250 and 500 Hz, or fast ripples (FR), appeared related to the epileptic focus whereas ripples (80-200 Hz) were not. We report high-frequency oscillations recorded with intracranial macroelectrodes in sev...

Predictability of EEG interictal spikes.

To determine whether EEG spikes are predictable, time series of EEG spike intervals were generated from subdural and depth electrode recordings from four patients. The intervals between EEG spikes were hand edited to ensure high accuracy and eliminate false positive and negative spikes. Spike rates (per minute) were generated from longer time series, but for these data hand editing was usually ...

High-resolution EEG: cortical potential imaging of interictal spikes.

BACKGROUND It is of clinical importance to localize pathologic brain tissue in epilepsy. Noninvasive localization of cortical areas associated with interictal epileptiform spikes may provide important information to facilitate presurgical planning for intractable epilepsy patients. METHODS A cortical potential imaging (CPI) technique was used to deconvolve the smeared scalp potentials into th...

Source Analysis of Interictal Spikes in EEG and MEG

Simultaneous EEG/MEG and ECoG source characterization of interictal spikes

For some TLE patients that do not respond the pharmacological treatment, epilepsy surgery is an option. In those cases, the determination of the location of the sources and the sequence in which they become active is of prime importance. In this paper, we investigate the interpretability and validity of dipole source localization based on EEG, MEG and simultaneous EEG+MEG for TLE interictal spi...